Labrador Tricuspid Valve DNA Study
North Carolina State University is looking for DNA samples from Labrador Retrievers for a genetic study that evaluates unique DNA changes that may be associated with the congenital heart disease, tricuspid valve dysplasia.
At this time, we would like to collect DNA samples from 100 Labrador Retrievers. We need DNA from both healthy Labrador Retrievers without heart disease and from Labradors with tricuspid valve dysplasia.
Ideally, the DNA would be from a wide number of families so we are hoping to get samples from as many different families as possible.
Thank you for your help!
Dr. Kate Meurs, North Carolina State University
Sample collection (cheek swab or blood acceptable)
Cheek swab: We would be happy to ship you a swab collection kit for you to swab your dog for DNA collection. Email Dr. Meurs to request a kit: firstname.lastname@example.org
Please ask your veterinarian or a veterinary technician to pull a blood sample into an EDTA Most veterinary hospitals have these readily available.
- 2-3 milliliters of blood should be collected into a standard EDTA tube (does not need to be refrigerated).
Please label tube well, with animal’s call name and family last name and send the samples to our lab via the address below.
Please return this form with your sample and mail to:
NCSU – College of Veterinary Medicine
ATTN: Veterinary Cardiac Genetics Laboratory
Research Bldg. 326
1060 William Moore Dr.
Raleigh, NC 27607
Blood drawn does not need to be mailed with ice packs or be shipped overnight. However, if possible please try to send the sample within a few days by standard mail.
Questions? Contact Info: Email: Kate_meurs@ncsu.edu or Phone: 919-513-6213
Thank you very much for your submitting a sample, we greatly appreciate it!
The Experience of a Previous “Silver Lab” Breeder by Mary Frances Clark
The dog on the left is what most people refer to as a “Silver Lab.” Her name is Sky. As you can see, Sky is hairless–not like a Labrador Retriever should be! She is affected by color dilution alopecia, which is a hair loss condition in dogs which are dilute. In “Labs,” dilutes are referred to as silver, charcoal, and champagne. Sky also has allergies and mast cell carcinoma (skin cancer).
My husband, then fiancé, and I purchased the two dogs you see in the photo. I was 23 years old and ignorant about Labradors. I believed what I read on silver breeders’ websites about the origin of the dilute gene supposedly being “inherent in the Lab gene pool,” and “no health issues.” I didn’t even know about health clearances when we bought these first two dogs.
I’ve learned much since acquiring our first two dogs. I did complete some health clearances on Sky. I bred her twice, producing two litters of 5 puppies. I had a litter of full dilutes by another silver I previously owned. (He was neutered and placed in a pet home shortly after the silver litter, which was an unintentional litter.) Sky was bred to a standard chocolate stud for her second litter. I informed the stud dog owner that Sky was silver when asking for stud service. I would not trick someone into breeding to a silver dog, as there are repercussions among fellow breeders for doing so, nor is it right to do so. Sky had complications and required a c-section and spay with this litter. I kept a female puppy from the litter. But, owners of some puppies from Sky’s first litter began telling me that they were having allergy and coat problems. I then decided to stop breeding dilutes fully and placed that puppy in a pet home. That was the end of my breeding dilutes. I do however still own Sky. She has temperament issues and developed the multiple health issues I mentioned above, so I did not feel it would be fair to her or anyone else to re-home her. She will stay here until she dies.
Breeding dilutes is a mistake I regret, but I cannot take it back. I regret it for several reasons. I regret producing unhealthy dogs, though at the time I did not realize they were going to be unhealthy. I regret breeding dogs that at some point had a mixed lineage to produce the dilute color. I regret it also because of all the drama and stress it has caused me and the issues it will cause me in my future efforts to breed quality, healthy, purebred Labrador Retrievers. I hope sharing my experience can help prevent others from making the same mistakes.
Blastomycosis on the Rise
This fungal disease, which readily infects dogs and people, typically starts out in the lungs but can go on to invade many tissues throughout the body. Identifying it quickly and implementing antifungal therapy can result in a good prognosis.
View the whole article here!